Method for the diagnosis, prognosis and treatment of breast cancer metastasis
US12312642B2 · kind B2 · utility
0Cited by
23References
20Claims
0Family size
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Key dates
| Filing date | Jul 26, 2021 |
| Grant date | May 27, 2025 |
| Priority date | — |
| Expiry date | Oct 18, 2041 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q2600/158
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to a method for the diagnosis or the prognosis of metastasis in breast cancer which comprises determining if the c-MAF gene is amplified in a primary tumor sample. Likewise, the invention also relates to a method for the diagnosis or the prognosis of metastasis in ER-breast cancer, as well as to a method for determining the tendency to develop bone metastasis with respect to metastasis in other organs, which comprise determining the c-MAF gene expression level. Finally, the invention relates to the use of a c-MAF inhibitor as therapeutic target for treating the ER-breast cancer metastasis.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.