Systems and methods for generating lead
US12312653B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Aug 15, 2024 |
| Grant date | May 27, 2025 |
| Priority date | — |
| Expiry date | Aug 15, 2044 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG21G1/001
- WIPO fieldChemical engineering
- WIPO sectorChemistry
Abstract
A method for separating a lead radioisotope from a mixture comprising the lead radioisotope and a radioisotope of radium or thorium is provided, along with a system comprising a plurality of chromatographic columns. The system can include a first cartridge having a lead-complexing media that preferentially binds the lead radioisotope over radioisotopes of radium or thorium, and a second cartridge having a weak cationic exchange media, where a pH of a loading solution used to load the second cartridge is pH2L, and a pH of an eluent used to elute the lead radioisotope from the second cartridge is pH2E, and pH2L is greater than pH2E. The system can also comprise further third and fourth cartridges with chromatographic media to extract and purify the lead radioisotope, to provide a purified solution of lead radioisotope that can be used for medical and other purposes, such as in the labeling of radiopharmaceutical compounds.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.