Operation of an injector of a sample separation device

US12313607B2 · kind B2 · utility

Assignee

• AGILENT TECHNOLOGIES, INC. · US

Inventors

• Thomas Ortmann · Ittersbach, DE
• Martin Seifried · Ettlingen, DE
• Sam Wouters · Schiftung, DE
• Irina Spuling · Karlsruhe, DE

Key dates

• Filing date: Feb 1, 2024
• Grant date: May 27, 2025
• Expiry date: Feb 1, 2044

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N2030/326
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

A sample separation device includes a separation path and a control unit. The separation path is between a fluid drive and a sample separation unit, and is configured to inject a fluidic sample in an injector path into a mobile phase in the separation path driven by the fluid drive to the sample separation unit for chromatographically separating the fluidic sample. The control unit is configured to control blocking the injector path or at least a partial path thereof, generating an overpressure in the blocked injector path or the partial path thereof by a pressure source, and subsequently fluidically coupling the injector path or the partial path thereof to a region of lower pressure than the overpressure to generate an expansion stroke for releasing unwanted components from the injector path.