Living tissue model device, vascular wall model, vascular wall model device and method of evaluating test substance
US12313625B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Dec 5, 2019 |
| Grant date | May 27, 2025 |
| Priority date | — |
| Expiry date | Mar 12, 2042 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/5064
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A living tissue model device includes: a first liquid compartment storing a liquid composition; a second liquid compartment storing a liquid composition; and a cell layered body disposed between the first liquid compartment and the second liquid compartment, as a partition between both compartments. A vascular wall model includes: a porous membrane having a honeycomb structure; a vascular endothelial cell layer disposed on one face of the porous membrane; and a smooth muscle cell layer, or a mesenchymal stem cell layer, disposed on another face of the porous membrane. A vascular wall model device includes: a first liquid compartment storing a liquid composition; a second liquid compartment storing a liquid composition; and a vascular wall model disposed between the first liquid compartment and the second liquid compartment, as a partition between both compartments. Applications of these models or model devices are also provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.