Lobaric acid derivative having PTP-1B inhibitory activity, preparation method therefor and use thereof
US12319641B2 · kind B2 · utility
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Key dates
| Filing date | Aug 14, 2020 |
| Grant date | Jun 3, 2025 |
| Priority date | — |
| Expiry date | Jul 25, 2042 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D321/10
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A lobamide compound according to an embodiment of the present disclosure is represented by Formula 1. The lobamide compound has excellent PTP-1B inhibitory activity that is far higher than that of conventional lobaric acid derivatives and which can be orally administered, and thus is very effective in the prevention or treatment of diabetes or obesity through oral administration.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.