Liver-specific viral promoters and methods of using the same
US12319924B2 · kind B2 · utility
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22Claims
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Key dates
| Filing date | May 14, 2021 |
| Grant date | Jun 3, 2025 |
| Priority date | — |
| Expiry date | Feb 14, 2044 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2830/008
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to promoters that function specifically or preferentially in the liver. These promoters are capable of enhancing liver-specific expression of genes. The invention also relates to expression constructs, vectors and cells comprising such liver-specific promoters, and to methods of their use. The present invention future relates to adeno-associated virus (AAV) gene therapy vectors comprising the liver-specific promoters, therapeutic agents comprising the liver-specific promoters, and methods using the same.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.