Genetic construct
US12319927B2 · kind B2 · utility
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Key dates
| Filing date | May 25, 2018 |
| Grant date | Jun 3, 2025 |
| Priority date | — |
| Expiry date | Jan 14, 2040 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2830/85
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A genetic construct comprises a promoter operably linked to a first coding sequence, which encodes tyrosine hydroxylase (TH), and a second coding sequence, which encodes GTP cyclohydrolase 1 (GCH1), wherein the second coding sequence is 3′ to the first coding sequence, and the first and second coding sequences are part of a single operon. The genetic construct does not encode aromatic amino acid decarboxylase (AADC).
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.