Conjugates of a factor VIII moiety having an oxime-containing linkage
US12324828B2 · kind B2 · utility
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Key dates
| Filing date | Feb 27, 2023 |
| Grant date | Jun 10, 2025 |
| Priority date | — |
| Expiry date | Feb 27, 2043 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC08G65/33396
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present disclosure provides conjugates comprising a Factor VIII moiety covalently attached via an oxime-containing linkage to a water-soluble polymer, such as for example, a polyethylene glycol polymer. Methods for preparing and for administering such conjugates, are also provided, as are water-soluble polymer oxyamine reagents useful for preparing the subject conjugates, among other things.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.