Hyaluronate fiber and manufacturing method thereof
US12324867B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Nov 27, 2020 |
| Grant date | Jun 10, 2025 |
| Priority date | — |
| Expiry date | Oct 14, 2043 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61L2430/34
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A high-strength hyaluronate fiber, suitable for use in a surgical suture, a lifting thread, a tissue-engineering scaffold, etc., and a manufacturing method thereof are proposed. The method includes (a) controlling a water content of a hyaluronate having a weight average molecular weight of 100-3,000 kDa to 50-95 wt % to prepare a hyaluronate paste, (b) melting the hyaluronate paste having a controlled water content at a temperature ranging from room temperature to 100° C., and then extruding the hyaluronate paste through a nozzle, and (c) drying the extruded spinning fluid to form a fiber. The hyaluronate fiber has the water content of 5-25 wt %, the tensile strength of 3 to 15 kg/mm2, and a smooth surface with small cracks, so that the hyaluronate fiber can be used for a surgical suture, a lifting thread, a filler for cosmetic surgery, a tissue-engineering scaffold, etc.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.