Patent · US Active

RXR agonist salt form, polymorphs thereof, and uses thereof

US12325685B2 · kind B2 · utility

0Cited by

3References

9Claims

0Family size

Assignee

Io Therapeutics, Inc · US

Inventors

Vidyasagar Vuligonda · Irvine, US
Martin E. Sanders · Spring, US
Shanming Kuang
Harsh Shah · Ahmedabad, IN

Key dates

Filing date	Jan 18, 2024
Grant date	Jun 10, 2025
Priority date	—
Expiry date	Jan 18, 2044

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07C2602/10
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

Provided herein are salt and solid forms of (2E,4E)-3-methyl-5-((1S,2S)-2-methyl-2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)cyclopropyl)penta-2,4-dienoic acid, including a Tris salt form of (2E,4E)-3-methyl-5-((1S,2S)-2-methyl-2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)cyclopropyl)penta-2,4-dienoic acid, and polymorphs thereof, methods of preparing the compounds, and their uses.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.