Patent · US Active

Open-top microfluidic devices and methods for simulating a function of a tissue

US12325846B2 · kind B2 · utility

0Cited by

4References

7Claims

0Family size

Assignee

President and Fellows of Harvard College · US

Inventors

Antonio Varone · Riverdale, US
Norman Wen · Dedham, US
Daniel Levner · Brookline, US
Richard Novak · Plainsboro, US
Lori McPartlin · North Billerica, US
Donald E. Ingber · Boston, US
Youngjae Choe · Somerville, US
Lian Leng · Cambridge, US
Justin Nguyen · Medford, US

Key dates

Filing date	Mar 13, 2024
Grant date	Jun 10, 2025
Priority date	—
Expiry date	Mar 13, 2044

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12M41/46
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

A device for simulating a function of a tissue includes a first structure, a second structure, and a membrane. The first structure defines a first chamber. The first chamber includes a matrix disposed therein and an opened region. The second structure defines a second chamber. The membrane is located at an interface region between the first chamber and the second chamber. The membrane includes a first side facing toward the first chamber and a second side facing toward the second chamber. The membrane separates the first chamber from the second chamber.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.