Patent · US Active

Electrostatic control of ionic environment in a droplet based platform for biological applications

US12325876B2 · kind B2 · utility

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14Claims
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Key dates

Filing dateSep 4, 2019
Grant dateJun 10, 2025
Priority date
Expiry dateSep 12, 2041

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12Q1/6806
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

A process and device for electrostatically controlling an ionic environment in a droplet, such as in a droplet-based platform including polymerase-chain reaction (PCR) applications. The process includes providing a chip that comprises at least a pair of electrodes, placing a salt-containing droplet on the chip, and then applying a bias across the electrodes to accumulate ions near surfaces of the electrodes, thereby depleting a bulk salt concentration in regions of the droplet away from the electrodes.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.