Patent · US Active

Treatment methods for ALS patients

US12329776B2 · kind B2 · utility

0Cited by

13References

11Claims

0Family size

Assignees

NEUVIVO, INC. · US
The Regents of the University of California · US

Inventors

Arasteh Ari Azhir · Los Altos, US
Michael S. McGrath · Burlingame, US
Bruce D. Forrest · Nyack, US
Leah Price · Carmiel, IL

Key dates

Filing date	Feb 10, 2023
Grant date	Jun 17, 2025
Priority date	—
Expiry date	Feb 10, 2043

Classification

Technology area (CPC G)Physics
CPC primaryG01N2800/2835
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Provided herein are methods and compositions for the treatment of ALS using chlorite or a pharmaceutical composition comprising sodium chlorite, for a target ALS patient population. Also provided herein are methods for identifying a target ALS patient population likely to be responsive to treatment with chlorite or a pharmaceutical composition comprising sodium chlorite, the methods including identifying ALS patients with elevated plasma C-reactive protein (CRP) levels and/or patients age 40-65, sporadic ALS pathology, or combinations thereof.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.