Process for preparing an aqueous dispersion of microparticles

US12330128B2 · kind B2 · utility

Assignee

• BASF SE

Inventors

• Marion Winkelmann · Ludwigshafen, DE
• Kerstin Muelheims · Ludwigshafen am Rhein, DE
• Ralph Tauber · Gerolsheim, DE
• Yannick Fuchs · Ingelfingen, DE
• Murat Cetinkaya · Heidelberg, DE
• Bernd Sachweh · Meckenheim, DE

Key dates

• Filing date: Oct 20, 2016
• Grant date: Jun 17, 2025
• Expiry date: Apr 20, 2037

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A01N2300/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Provided herein is a process for preparing an aqueous dispersion of microparticles containing a water-insoluble, solid, non-polymeric, organic active or functional material (M) and an aminoplast resin (A) which surrounds or embeds material (M). The process includes the following steps: i) providing an aqueous slurry of the material (M) in the form of coarse particles; ii) subjecting the aqueous slurry to shear forces such that the coarse particles of the material (M) are comminuted and an aqueous suspension of fine particles of the material (M) is obtained; and iii) performing a polycondensation of an aminoplast pre-condensate during step (ii) or in the aqueous suspension of the fine particles of the material (M) obtained in step (ii); wherein step (ii) is performed in the presence of at least one protective colloid and in the presence of at least a portion of the aminoplast pre-condensate subjected to the polycondensation of step (iii).