Site-specific serine ADP-ribosylated proteins and peptides and method for producing the same
US12331074B2 · kind B2 · utility
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16Claims
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Key dates
| Filing date | Sep 17, 2019 |
| Grant date | Jun 17, 2025 |
| Priority date | — |
| Expiry date | Aug 21, 2042 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K1/36
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention relates to a method for producing a site -specifically serine ADP-ribosylated protein or peptide being, comprising: (a) subjecting a protein or peptide comprising or consisting of an amino acid sequence comprising two or more serines, wherein at least one serine is phosphorylated and at least one serine is non-phosphorylated, to a serine ADP-ribosylation reaction. The present invention also relates to a site-specifically serine ADP-ribosylated protein or peptide produced by the method of the invention.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.