Anti-MS4A4A antibodies and methods of use thereof

US12331111B2 · kind B2 · utility

Assignee

• Alector LLC

Inventors

• Philip Kong · San Francisco, US
• Herve Rhinn · New York, US
• Tina SCHWABE · San Francisco, US
• Angie Yee · San Francisco, US
• Ilaria TASSI · San Francisco, US
• Muhammad Abbas Alhawagri · San Francisco, US
• Arnon Rosenthal · Woodside, US

Key dates

• Filing date: Aug 19, 2022
• Grant date: Jun 17, 2025
• Expiry date: Dec 16, 2043

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K2317/92
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

The present disclosure is generally directed to compositions that include antibodies, e.g., monoclonal, antibodies, antibody fragments, etc., that specifically bind a MS4A4A polypeptide, e.g., a mammalian MS4A4A or human MS4A4A, and use of such compositions in preventing, reducing risk, or treating an individual in need thereof.