Patent · US Active

Polynucleotides

US12331331B2 · kind B2 · utility

0Cited by
6References
7Claims
0Family size

Assignee

Inventors

Key dates

Filing dateFeb 4, 2020
Grant dateJun 17, 2025
Priority date
Expiry dateFeb 18, 2040

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12Y302/01045
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention relates to polynucleotides comprising a GBA nucleotide sequence that encodes a GCase protein or fragment thereof and wherein a portion of the coding sequence is not wild type. The present invention further relates to viral particles comprising a recombinant genome comprising the polynucleotide of the invention, compositions comprising the polynucleotides or viral particles, and methods and uses of the polynucleotides, viral particles or compositions.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.