Patent · US Active

Digital analysis of blood samples to determine efficacy of cancer therapies for specific cancers

US12331363B2 · kind B2 · utility

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8References
15Claims
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Key dates

Filing dateMay 27, 2022
Grant dateJun 17, 2025
Priority date
Expiry dateJun 29, 2042

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12Q2600/158
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

This disclosure relates to new assay methods for analysis of RNA, e.g., from circulating tumor cells (CTCs), tumor-specific exosomes, or tumor-specific cell-free RNA, in a subject's blood sample to determine an expression level of one or more lineage markers in the blood sample, wherein the expression level of a specific one or more lineage markers is predictive of progression-free survival and overall survival for a specific anti-cancer treatment regimen in that subject.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.