Patent · US Active

Method and system for simultaneous mapping of quantitative MRI parameters using a T2 prepared inversion

US12336802B2 · kind B2 · utility

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Key dates

Filing dateApr 14, 2023
Grant dateJun 24, 2025
Priority date
Expiry dateJun 24, 2043

Classification

  • Technology area (CPC G)Physics
  • CPC primaryG01R33/56366
  • WIPO fieldMeasurement
  • WIPO sectorInstruments

Abstract

A qMRI system and method map qMRI parameters of a biological object. The method includes performing, by the qMRI system, N scans wherein each scan, includes: performing T2-prepared inversion pulse series, each followed by readout blocks, each magnetization preparation RF pulse series is a T2-prepared inversion pulse series containing multiple pulses and an inter-pulse duration, for varying to obtain different T2 weightings; and acquiring, by the MRI system and during each readout block of an MRI, a recovery signal generated by a part of the biological object, wherein for each readout block, an MRI signal is acquired by the MRI system at different inversion times. An image of the part is reconstructed for and from each MRI signal. A voxel-wise signal is created by concatenating intensity values for a same voxel for the reconstructed images. A physical model is fitted to the concatenated intensity values to obtain a qMRI map.

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