Patent · US Active

Combination therapies

US12336995B2 · kind B2 · utility

0Cited by
9References
36Claims
0Family size

Assignee

Inventors

Key dates

Filing dateSep 9, 2019
Grant dateJun 24, 2025
Priority date
Expiry dateFeb 5, 2041

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07K16/2863
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention relates to combination therapies for treating KRas G12C cancers. In particular, the present invention relates to methods of treating cancer in a subject in need thereof, comprising administering to the subject a therapeutically effective amount of a combination of a pan ErbB family inhibitor and a KRAS G12C inhibitor of Formula (I), Formula (I-A) or Formula (I-B), pharmaceutical compositions comprising a therapeutically effective amounts of the inhibitors, kits comprising the compositions and methods of use therefor.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.