Peptides and compounds that bind to elongation initiation factor 4E
US12338296B2 · kind B2 · utility
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Key dates
| Filing date | Mar 30, 2020 |
| Grant date | Jun 24, 2025 |
| Priority date | — |
| Expiry date | Aug 2, 2042 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A peptide that binds to elongation initiation factor 4E (eIF4E) comprising the amino acid sequence CEX1GX2X3X4X5C (SEQ ID NO: 1), where X1 is an amino acid selected from the group consisting of threonine (T), methionine (M) or leucine (L), X2 and X3 is an amino acid selected from the group consisting of phenylalanine (F), modified phenylalanine and tyrosine (Y), X4 and X5 is any amino acid, wherein the two cysteine residues are joined by a disulphide bond. Further, pharmaceutical compositions and uses of the peptide, and pharmaceutical compositions are provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.