Patent · US Active

Microbial consortia producing dipicolinic acid and methods for selecting microbes for co-formulation with carriers

US12342825B2 · kind B2 · utility

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3References
15Claims
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Key dates

Filing dateJun 5, 2019
Grant dateJul 1, 2025
Priority date
Expiry dateFeb 13, 2042

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12R2001/61
  • WIPO fieldBasic materials chemistry
  • WIPO sectorChemistry

Abstract

Methods for selecting a microbe for co-formulation with a carrier are provided. In some examples, the methods include identifying a microbe that comprises one or more dipicolinic acid (DPA) synthase genes, a microbe that expresses one or more DPA synthase proteins, and/or a microbe that produces DPA; and selecting the microbe for co-formulation with a carrier. The methods optionally include co-formulating the selected microbe with the carrier. In some examples, the methods include detecting one or more DPA synthase genes or one or more DpaA and/or DpaB proteins in a microbe. In other examples, the methods include detecting DPA in a microbe or medium containing a microbe, for example, utilizing a fluorescence assay. Microbial compositions including one or more microbes that comprise one or more DPA synthase genes, express one or more DPA synthase proteins and/or produce DPA are also provided.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.