Use of stem cells produced by stem cell generator in treatment of hematopoietic damage

US12343448B2 · kind B2 · utility

Assignee

• East China University of Science and Technology · CN

Inventors

• Changsheng Liu · State College, US
• Kai-I Dai · Taoyuan, TW
• Jing Wang · Beijing, CN
• Guilong Li · Shanghai, CN
• Qinghao ZHANG · Zhejiang, CN
• Shunshu Deng · Shanghai, CN

Key dates

• Filing date: Jan 21, 2020
• Grant date: Jul 1, 2025
• Expiry date: Jul 4, 2042

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61L2430/02
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Disclosed is a stem cell generator for the generation of organoids after the development of biological materials loaded with active substances which are implanted into an animal or a human body. The active substances are mesenchymal stem cells, bone morphogenetic protein-2 or bone morphogenesis protein-7, other growth factors/polypeptides or growth factors/polypeptide combinations having the ability of inducing bone regeneration, or combinations thereof. The stem cell generator contains various types of blood cells and hematopoietic progenitor/stem cells having complete functions. The produced stem cells are used for treating hematopoietic damage, and can treat bone marrow failure and leukemia caused by radiotherapy/chemotherapy.