Patent · US Active

Imidazolonylquinoline compounds and therapeutic uses thereof

US12344604B2 · kind B2 · utility

0Cited by

1References

8Claims

0Family size

Assignee

Merck Patent GmbH · DE

Inventors

Thomas Fuchss · Bensheim, DE
Axel Becker · Altrip, DE
Holger Kubas · Bad Homburg vor der Höhe, DE
Ulrich Graedler · Weinheim, DE

Key dates

Filing date	Mar 25, 2020
Grant date	Jul 1, 2025
Priority date	—
Expiry date	Jun 9, 2042

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07B2200/05
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

Atropisomers, solid forms, salt forms, and deuterated derivatives of the ATM inhibitor 8-(1,3-Dimethyl-1H-pyrazol-4-yl)-1-(3-fluoro-5-methoxypyridin-4-yl)-7-methoxy-3-methyl-1,3-dihydroimidazo[4,5-c]quinolin-2-one as well as compositions thereof are provided. The stable atropisomers do not interconvert and are represented by the following formulae.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.