Patent · US Active

Human intestinal epithelium model and method for preparing same

US12344862B2 · kind B2 · utility

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5Claims
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Key dates

Filing dateNov 3, 2020
Grant dateJul 1, 2025
Priority date
Expiry dateJan 8, 2042

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12N2533/90
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention relates to a method for preparing a human intestinal epithelial model. The human intestinal epithelial model, prepared by the method according to the present invention, has all characteristics of goblet cells, enteroendocrine cells, and Paneth cells, and thus can highly mimic the function of actual human intestinal cells, so that the human intestinal epithelial model can be effectively used for development of new drugs, evaluation of drug absorption and toxicity, or evaluation of engraftment of intestinal microorganisms, or as a composition for in vivo transplantation.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.