Compositions and methods for detection of genomic variations
US12344886B2 · kind B2 · utility
0Cited by
4References
16Claims
0Family size
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Key dates
| Filing date | Jun 14, 2018 |
| Grant date | Jul 1, 2025 |
| Priority date | — |
| Expiry date | Nov 18, 2039 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q2565/631
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention concerns compositions, kits and methods for genetic variation detection and classification. These methods combine the specificity of a ligation reaction with the single-molecule sensitivity of nanopore biosensors. This invention can achieve clinical detection of many diseases, including bacterial infections and cancer entities, by identification of specific genetic alterations.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.