Systems and methods for multimodal neural sensing

US12350010B2 · kind B2 · utility

Assignee

• Regents of the University of Minnesota · US

Inventors

• Suhasa Kodandaramaiah · Minneapolis, US
• Leila Ghanbari · Minneapolis, US
• Daniel Schulman · Hillsboro, US
• Michael C. McAlpine · Minneapolis, US
• Sarah Swisher · Corona, US
• Preston Donaldson · Minneapolis, US

Key dates

• Filing date: Dec 4, 2020
• Grant date: Jul 8, 2025
• Expiry date: Sep 10, 2043

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61F2002/30985
• WIPO field: Medical technology
• WIPO sector: Instruments

Abstract

A system and method is provided for imaging and monitoring a tissue, such as a cerebral cortex, of a subject. Access to imaging a tissue, such as cerebral cortex, may be provided by removing a portion of a bone, such as a portion of a skull of the subject. A prosthesis, such as an optically transparent prosthesis, may be used to replace the portion of the skull removed and may be conformed to the same 3D contour of the bone that was removed. A data acquisition system, such as an imaging system, may then be affixed to the skull prosthesis and may be used to acquire image data of the tissue of the subject at high spatial and temporal resolution and without interference from intervening bone material.