Patent · US Active

Methods and compositions for treating motor neuron diseases

US12350283B2 · kind B2 · utility

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1References
8Claims
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Key dates

Filing dateFeb 25, 2020
Grant dateJul 8, 2025
Priority date
Expiry dateAug 1, 2042

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61K31/573
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Provided herein are methods and compositions related to treating motor neuron diseases, such as ALS, in a subject by administering to the subject (e.g., orally administering to the subject) a composition comprising nicotinamide riboside, pterostilbene and a phosphodiesterase (PDE) inhibitor, including a PDE4 inhibitor such as ibudilast, and also including a thiol/cysteine donor, such as acetylcysteine.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.