Patent · US Active

Induction method for macrophage, anti-inflammatory macrophage-inducing agent, and pharmaceutical composition

US12350293B2 · kind B2 · utility

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8Claims
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Key dates

Filing dateMar 6, 2020
Grant dateJul 8, 2025
Priority date
Expiry dateFeb 26, 2042

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12N2502/1358
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

An induction method for a macrophage is provided, in which macrophages are cultured in the presence of exosomes produced from a mesenchymal stem cell to which interferon gamma has been added and are induced into anti-inflammatory macrophages. An anti-inflammatory macrophage-inducing agent includes exosomes produced from a mesenchymal stem cell to which interferon gamma has been added, as an active component. A pharmaceutical composition contains the inducing agent.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.