Induction method for macrophage, anti-inflammatory macrophage-inducing agent, and pharmaceutical composition
US12350293B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Mar 6, 2020 |
| Grant date | Jul 8, 2025 |
| Priority date | — |
| Expiry date | Feb 26, 2042 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2502/1358
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
An induction method for a macrophage is provided, in which macrophages are cultured in the presence of exosomes produced from a mesenchymal stem cell to which interferon gamma has been added and are induced into anti-inflammatory macrophages. An anti-inflammatory macrophage-inducing agent includes exosomes produced from a mesenchymal stem cell to which interferon gamma has been added, as an active component. A pharmaceutical composition contains the inducing agent.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.