Binding agent and assay for PIVKA

US12351647B2 · kind B2 · utility

Assignee

• Roche Diagnostics Operations, Inc. · US

Inventors

• Bernhard Eckert · Weilheim, DE
• Michael Gerg · Munich, DE
• Johann Karl · Peißenberg, DE
• Martin Kaufmann · Weilheim, DE
• Julia Riedlinger · Ottobrunn, DE
• Magdelena Swiatek-de-Lange · Penzberg, DE
• Lars Hillringhaus · Penzberg, DE
• Klaus Hirzel · Baierbrunn, DE
• Marcus-Rene Lisy · Geretsried, DE

Key dates

• Filing date: Aug 24, 2022
• Grant date: Jul 8, 2025
• Expiry date: Nov 20, 2042

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N2333/745
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

The present disclosure relates to specific binding agents binding to different PIVKA-II forms as compared to antibodies known so far in the art. The present disclosure also relates to methods of using the specific binding agents to detect the presence of PIVKA-II.