Antibodies binding to fibroblast activation protein alpha and death receptor 4
US12351650B2 · kind B2 · utility
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21References
34Claims
0Family size
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Key dates
| Filing date | Jun 26, 2024 |
| Grant date | Jul 8, 2025 |
| Priority date | — |
| Expiry date | Jun 26, 2044 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2800/52
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to a multispecific antibody comprising at least a FAPα binding region comprising a first heavy chain variable region and a first light chain variable region; and a DR4 binding region comprising a second heavy chain variable region and a second light chain variable region. The invention further provides pharmaceutical compositions comprising the antibodies and use of the antibodies for therapeutic and diagnostic procedures, in particular in cancer therapy.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.