Pharmaceutical composition for drug delivery

US12357573B2 · kind B2 · utility

Assignee

• OREXO AB · SE

Inventors

• Jonas Sävmarker · Uppsala, SE
• Robert Rönn · Uppsala, SE
• Andreas Fischer · Castro Valley, US

Key dates

• Filing date: Jun 30, 2023
• Grant date: Jul 15, 2025
• Expiry date: Jun 30, 2043

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K9/0078
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

According to the invention, there is provided a pharmaceutically-acceptable composition which is preferably in the form of a spray-dried powder comprising a mixture of: Compositions are suitable for, for example, transmucosal drug delivery, including sublingual and nasal delivery. In the case of nasal delivery, said compositions may be loaded into single- or multiple-use nasal applicators. Preferred pharmaceutically-acceptable carriers in this regard include lactose or trehalose and dextrins (e.g. cyclodextrins or maltodextrins), which may be spray-dried together in combination. Compositions may further comprise one or more alkyl saccharides. Preferred alkyl saccharides include sucrose esters, such as sucrose monolaurate.