Methods of making lipid nanoparticles
US12357575B2 · kind B2 · utility
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13Claims
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Key dates
| Filing date | Jun 21, 2023 |
| Grant date | Jul 15, 2025 |
| Priority date | — |
| Expiry date | Jun 21, 2043 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB82Y5/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The disclosure features novel methods of producing nucleic acid lipid nanoparticle (LNP) compositions employing a modifying agent after formation of a precursor nucleic acid lipid nanoparticle, the produced compositions thereof, and methods involving the nucleic acid lipid nanoparticles useful in the delivery of therapeutics and/or prophylactics, such as a nucleic acid, to mammalian cells or organs to, for example, to regulate polypeptide, protein, or gene expression.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.