Sublingual epinephrine compositions including pH-modifying excipients and penetration enhancers and methods for use thereof
US12357591B2 · kind B2 · utility
0Cited by
18References
5Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Oct 18, 2019 |
| Grant date | Jul 15, 2025 |
| Priority date | — |
| Expiry date | Dec 11, 2041 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P37/08
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention provides sublingual epinephrine compositions including epinephrine fine particles formulated with pH-modifying excipients and penetration enhancers. The sublingual compositions are used to control absorption of epinephrine at the site of delivery in an oral cavity. The invention also provides methods for therapeutic use of the sublingual compositions for treatment of conditions responsive to epinephrine and/or for increasing sublingual bioavailability of epinephrine.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.