Patent · US Active

E. coli FimH mutants and uses thereof

US12357681B2 · kind B2 · utility

0Cited by

28References

20Claims

0Family size

Assignee

PFIZER INC. · US

Inventors

Ye Che · Groton, US
Laurent Oliver Chorro · New York, US
Robert George Konrad Donald · South Orange, US
Matthew Curtis Griffor · Preston, US
Natalie Clare Silmon de Monerri · New York, US

Key dates

Filing date	Dec 17, 2021
Grant date	Jul 15, 2025
Priority date	—
Expiry date	Dec 17, 2041

Classification

Technology area (CPC Y)Emerging Cross-Sectional Technologies
CPC primaryY02A50/30
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

This disclosure relates to the design of E. coli mutated FimH polypeptides that result in improved biochemical properties and immunogenicity, compositions comprising such polypeptides, and uses thereof.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.