Patent · US Active

Negatively charged peg-lipid conjugates

US12357705B2 · kind B2 · utility

0Cited by
14References
20Claims
0Family size

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Key dates

Filing dateNov 8, 2019
Grant dateJul 15, 2025
Priority date
Expiry dateAug 11, 2042

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12N15/88
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The invention provides PEG-conjugated lipids of formula (I): A-B-C (I) wherein A, B, and C have any of the values defined in the specification, as well as compositions comprising the PEG-conjugated lipids of formula (I), nucleic acid lipid nanoparticles comprising the PEG-conjugated lipids of formula (I), and methods of using the PEG-conjugated lipids of formula (I), the compositions, and the nucleic acid nanoparticles.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.