Implantable medical systems, devices, and methods for affecting cardiac function through diaphragm stimulation, and for monitoring diaphragmatic health
US12357825B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Feb 5, 2024 |
| Grant date | Jul 15, 2025 |
| Priority date | — |
| Expiry date | Feb 5, 2044 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61N1/36578
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
Devices, systems and methods provide forms of asymptomatic diaphragmatic stimulation (ADS) therapy that affect pressures within the intrathoracic cavity, including: 1) dual-pulse ADS therapy, during which a first ADS pulse is delivered during a diastolic phase of a cardiac cycle and a second ADS pulse is delivered during a systolic phase, 2) paired-pulse ADS therapy, during which a first ADS pulse is delivered, closely followed by a second ADS pulse, with the second ADS pulse functioning to extend or enhance a phase of a transient, partial contraction of the diaphragm, and 3) multiple-pulse ADS therapy, during which a stream of ADS pulses is delivered, wherein the time between pulses is based on heart rate. Devices, systems and methods also monitor electromyography (EMG) activity of the diaphragm relative to baseline activity to assess the health of a diaphragm subject to ADS therapy and to adjust ADS therapy parameters or sensing parameters.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.