Extremely low duty-cycle activation of the cholinergic anti-inflammatory pathway to treat chronic inflammation
US12357826B2 · kind B2 · utility
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Key dates
| Filing date | Dec 22, 2017 |
| Grant date | Jul 15, 2025 |
| Priority date | — |
| Expiry date | Dec 22, 2037 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61N1/37205
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
Described herein are systems and methods for applying extremely low duty-cycle stimulation sufficient to treat chronic inflammation using feedback to adjust the off times between stimulations. In particular, the feedback include an assessment of the level of inflammation by the patient or the healthcare provider, or by measure the level of an inflammatory analyte or biomarker, or by detecting nerve activity correlated with inflammation.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.