Patent · US Active

Preparation method and use of pyrazole compound containing 1-(3,4-dimethoxyphenyl)-β-carboline unit

US12358914B2 · kind B2 · utility

0Cited by

0References

2Claims

0Family size

Assignee

Nanjing University · CN

Inventors

Hong Dai · 安丰镇, CN
Heyi Miao · 安丰镇, CN
Meiling Huang · 安丰镇, CN
Cheng Qian · Nanhu, CN
Dandan Zheng · 安丰镇, CN
Yan Zhang · Fort Washington, US
Yang Wang · Kingston, CA
Yong-Chien Ling · Hsinchu, TW
Beibei Zhou · 安丰镇, CN
Haijun Zhang · Beijing, CN

Key dates

Filing date	Aug 25, 2021
Grant date	Jul 15, 2025
Priority date	—
Expiry date	Dec 14, 2043

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61P35/00
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The disclosure relates to a preparation method and use of a pyrazole compound containing 1-(3,4-dimethoxyphenyl)-β-carboline unit. The pyrazole compound is prepared by reacting pyrazole aldehyde and 1-(3,4-dimethoxyphenyl)-β-carboline acylhydrazine. The pyrazole compound containing 1-(3,4-dimethoxyphenyl)-β-carboline unit has good inhibitory activity against tumor cell HGC-27. The pyrazole compound could be used in the preparation of anti-tumor drugs.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.