Methods of obtaining tumor-specific T cell receptors
US12358967B2 · kind B2 · utility
0Cited by
13References
20Claims
0Family size
Assignees
Inventors
Key dates
| Filing date | Jun 17, 2022 |
| Grant date | Jul 15, 2025 |
| Priority date | — |
| Expiry date | Jun 17, 2042 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2710/20034
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Provided methods of obtaining a plurality of T cell receptors specifically recognizing a target tumor antigen peptide from an individual that has clinically benefitted from an immunotherapy, such as Multiple Antigen Specific Cell Therapy. Also provided tumor-specific TCRs, engineered immune cells expressing the TCRs and methods of treating a disease using the engineered immune cells.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.