Anti-CD6 antibody-growth factor complex for treating autoimmune diseases
US12358998B2 · kind B2 · utility
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20Claims
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Key dates
| Filing date | Jul 1, 2019 |
| Grant date | Jul 15, 2025 |
| Priority date | — |
| Expiry date | Jun 22, 2042 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/75
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Provided herein are, inter alia, anti-CD6 antibody-growth factor complexes including an anti-CD6 antibody portion bound to a growth factor protein (e.g., EGF) through a linker, which may be cleavable by a protease (e.g., diabetic microenvironment specific protease). The compositions provided herein are, inter alia, useful for the treatment of autoimmune diseases (e.g., type I diabetes).
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.