Device, method and composition for transfection of cells with nucleic acids
US12359157B2 · kind B2 · utility
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13Claims
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Key dates
| Filing date | May 21, 2021 |
| Grant date | Jul 15, 2025 |
| Priority date | — |
| Expiry date | May 21, 2041 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N15/88
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Disclosed are a method, a composition and a device for the introduction of exogenous nucleic acids into eukaryotic cells by non-viral vectors (non-viral transfection). The method according to the invention is based on application of a high-frequency oscillatory motion to a solution containing nucleic acids and cationic polymers or lipids to obtain particles (complexes) with high transfection efficiency.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.