Polyanionic acids to improve recovery and minimize system loss
US12359191B2 · kind B2 · utility
0Cited by
6References
13Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jan 17, 2024 |
| Grant date | Jul 15, 2025 |
| Priority date | — |
| Expiry date | Jan 17, 2044 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2030/8836
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present technology relates to a method of separating a sample comprising oligonucleotides. The method includes injecting a polyphosphonic acid at a concentration of between about 0.01 M to about 1 M into the sample comprising oligonucleotides. The method also includes flowing the sample and polyphosphonic acid through a liquid chromatography column and separating the oligonucleotides.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.