Patent · US Active

Chemical platform assisted proximity capture (CAP-C)

US12359242B2 · kind B2 · utility

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25Claims
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Assignee

Inventors

Key dates

Filing dateMay 8, 2019
Grant dateJul 15, 2025
Priority date—
Expiry dateNov 15, 2042

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12Q2565/518
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

Certain embodiments are directed to compositions and methods for capture of elements in physical proximity. In certain aspects the methods comprise (a) contacting a target with a functionalized scaffold or capture agent that comprises activatable cross-linking moieties to form a target/scaffold mixture; (b) exposing the target/scaffold mixture to an activator to activate the cross-linking moieties of the dendrimer and form a cross-linked target/scaffold complex; (c) isolating the target/scaffold complexes; and (d) identify portions of the target or targets that are cross linked with the scaffold.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.