Methods of performing GUIDE-Seq on primary human T cells
US12359247B2 · kind B2 · utility
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17Claims
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Key dates
| Filing date | Aug 26, 2020 |
| Grant date | Jul 15, 2025 |
| Priority date | — |
| Expiry date | Jan 2, 2042 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2310/315
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Disclosed herein are methods for identifying the effects, including off target effect, of genomic modification of primary cells. These methods are performed with high accuracy suitable for validating therapeutic T-cell engineering approaches.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.