Methods and compositions for the diagnosis, prophylaxis and treatment of Lyme disease
US12364744B2 · kind B2 · utility
Assignee
Inventor
Key dates
| Filing date | Nov 24, 2021 |
| Grant date | Jul 22, 2025 |
| Priority date | — |
| Expiry date | Nov 24, 2041 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2800/26
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Reagents that include certain identified peptides derived from B. burgdorferi proteins, or nucleic acid sequences encoding same are useful in the diagnosis of Lyme borreliosis (Lyme Disease) in infected subject are disclosed herein. Such reagents can also include nucleic acid sequences encoding the peptides. Pharmaceutical compositions useful for the treatment or prophylaxis of B. burgdorferi infection include certain peptides derived from B. burgdorferi proteins, or nucleic acid sequences encoding same. Methods of treating or preventing Lyme borreliosis (Lyme Disease) include administering effective amount of such pharmaceutical compositions. An antibody independent prophylactic pharmaceutical composition comprises a sonicate of B. burgdorferi bacterium; and methods of treating or preventing Lyme borreliosis include administering effective amounts of that sonicate composition are also disclosed herein.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.