Solid form of diaminopyrimidine compound or hydrate thereof, preparation method therefor, and application thereof

US12365665B2 · kind B2 · utility

Assignee

• BEIJING TIDE PHARMACEUTICAL CO., LTD. · CN

Inventors

• CheungLing Cheng · Beijing, CN
• Yanping Zhao · Beijing, CN
• Hongjun Wang · Ningbo City, CN
• Zewang Feng · Beijing, CN
• Huai HUANG · Beijing, CN
• Kai Liu · Beijing, CN
• Xuelian Liu · Sunnyvale, US
• Jianmei Pang · Beijing, CN
• Nana Tian · Shanghai, CN
• Xichao Chen · Hangzhou City, CN
• Shenzhen Fu · Beijing, CN
• Jie Meng · Los Angeles, US
• Liying ZHOU · Beijing, CN
• Yanan Liu · Beijing, CN

Key dates

• Filing date: Apr 29, 2020
• Grant date: Jul 22, 2025
• Expiry date: Jun 1, 2042

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07B2200/13
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention relates to a solid form of 5-((2-ethynyl-5-isopropylpyridin-4-yl)oxy)pyrimidine-2,4-diamine or a hydrate thereof, a method for preparing the solid form, a pharmaceutical composition comprising the solid form, and a use of the solid form for the prevention or treatment of a disease modulated by P2X3 and/or P2X2/3 receptor antagonists.