Patent · US Active

Nitrile derivative that acts as inhibitor of dipeptidyl peptidase 1 and use thereof

US12365673B2 · kind B2 · utility

0Cited by
1References
6Claims
0Family size

Assignee

Inventors

Key dates

Filing dateSep 15, 2023
Grant dateJul 22, 2025
Priority date
Expiry dateOct 4, 2043

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07F9/6527
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

Disclosed is a nitrile derivative compound represented by formula (I), a stereoisomer, a deuterated product, a co-crystal, a solvate or a pharmaceutically acceptable salt thereof, wherein each group is as defined in the description. The compound has dipeptidyl peptidase 1 inhibitory activity and can be used to prepare a drug for treating diseases including obstructive airway diseases, bronchiectasis, cystic fibrosis, asthma, emphysema, and chronic obstructive pulmonary diseases.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.