Methods for increasing resolution of spatial analysis
US12365935B2 · kind B2 · utility
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402References
18Claims
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Key dates
| Filing date | Oct 21, 2022 |
| Grant date | Jul 22, 2025 |
| Priority date | — |
| Expiry date | Oct 21, 2042 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2474/20
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Provided herein are methods for capturing an analyte from a first region of interest of a biological sample on a substrate, where the biological sample comprises the first region of interest and a second region, and where the method includes contacting the second region with a sealant in order to create a hydrophobic seal thereby preventing an interaction between an analyte from the second region with a capture domain of a capture probe.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.