Patent · US Active

Compositions and methods for treating malaria

US12370183B2 · kind B2 · utility

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0References
20Claims
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Key dates

Filing dateFeb 16, 2021
Grant dateJul 29, 2025
Priority date
Expiry dateSep 1, 2042

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY02A50/30
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Disclosed are methods of treating malaria with tetrahydrobenzonaphtyridine carboxanilide (TBN) derivatives and related pyrrolinones and hydrolysis products thereof. These compounds are active against Plasmodium falciparum strains that are resistant to multiple drugs currently on the market. The present invention further relates to novel compounds and pharmaceutical compositions comprising such compounds.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.